Ranking players is always the most challenging in week 1. You just never know how a team -- or an individual player -- will perform compared to last season. The best approach when selecting your starting line-up for week one is to go with established player. For instance, if you're deciding between Hines Ward and Johnny Knox, pick Ward. He has a long track record of being a solid fantasy player, and he should get a lot of targets. As the season goes on, this may change as Ward's role in the offense diminishes and Knox grows as a WR.
With that said, here are the week one rankings for quarterbacks, running backs and wide receivers:
QB
1. Drew Brees vs. Minnesota
2. Peyton Manning at Houston Texans
3. Aaron Rodgers at Philadelphia Eagles
4. Tom Brady vs. Cincinnati Bengals
5. Matt Schaub vs. Indianapolis Colts
6. Philip Rivers at Kansas City Chiefs
7. Kevin Kolb vs. Green Bay Packers
8. Jay Cutler vs. Detroit Lions
9. Brett Favre at New Orleans Saints
10. Carson Palmer at New England Patriots
11. Tony Romo at Washington Redskins
12. Eli Manning vs. Carolina Panthers
13. Derek Anderson vs. St. Louis Rams
14. Kyle Orton at Jacksonville Jaguars
15. Vince Young vs. Oakland Raiders
16. Alex Smith at Seattle Seahawks
17. Donovan McNabb vs. Dallas Cowboys
18. Joe Flacco at New York Jets
19. Chad Henne at Buffalo Bills
20. Matt Ryan at Pittsburgh Steelers
RB
1. Adrian Peterson at New Orleans Saints
2. Chris Johnson vs. Oakland Raiders
3. Frank Gore at Seattle Seahawks
4. Maurice Jones-Drew vs. Denver Broncos
5. Steven Jackson vs. Arizona Cardinals
6. Jerome Harrison vs. Tampa Bay Buccaneers
7. Arian Foster vs. Indianapolis Colts
8. Rashard Mendenhall vs. Atlanta Falcons
9. Beanie Wells at St. Louis Rams
10. Ray Rice at New York Jets
11. DeAngelo Williams at New York Giants
12. Cedric Benson at New England Patriots
13. Ryan Mathews at Kansas City Chiefs
14. Joseph Addai at Houston Texans
15. Ronnie Brown at Buffalo Bills
16. Ryan Grant at Philadelphia Eagles
17. Cadillac Williams vs. Cleveland Browns
18. Jonathan Stewart at New York Giants
19. Matt Forte vs. Detroit Lions
20. Michael Turner at Pittsburgh Steelers
21. Pierre Thomas vs. Minnesota Vikings
22. Jamaal Charles vs. San Diego Chargers
23. Shonn Green vs. Baltimore Ravens
24. Jahvid Best at Chicago Bears
25. LeSean McCoy vs. Green Bay Packers
26. Reggie Bush vs. Minnesota Vikings
27. Ahmad Bradshaw vs. Carolina Panthers
28. Tim Hightower at St. Louis Rams
29. Felix Jones at Washington Redskins
30. Ricky Williams at Buffalo Bills
31. Marion Barber III at Washington Redskins
32. CJ Spiller vs. Miami Dolphins
33. Brandon Jacobs vs. Carolina Panthers
34. Clinton Portis vs. Dallas Cowboys
35. Chester Taylor vs. Detroit Lions
36. Darren McFadden at Tennessee Titians
37. Justin Forsett vs. San Francisco 49ers
38. Correll Buckhalter at Jacksonville Jaguars
39. Fred Taylor vs. Cincinnati Bengals
40. Peyton Hillis at Tampa Bay Buccaneers
WR/TE
1. Andre Johnson vs. Indianapolis Colts
2. Reggie Wayne at Houston Texans
3. Larry Fitzgerald at St. Louis Rams
4. DeSean Jackson vs. Green Bay
5. Calvin Johnson at Chicago Bears
6. Randy Moss vs. Cincinnati Bengals
7. Miles Austin at Washington Redskins
8. Greg Jennings at Philadelphia Eagles
9. Chad OchoCinco at New England Patriots
10. Marques Colston vs. Minnesota Vikings
11. Antonio Gates at Kansas City Chiefs
12. Brandon Marshall at Buffalo Bills
13. Vernon Davis at Seattle Seahawks
14. Hines Ward vs. Atlanta Falcons
15. Pierre Garcon at Houston Texans
16. Robert Meachem vs. Minnesota Vikings
17. Dallas Clark at Houston Texans
18. Roddy White at Pittsburgh Steelers
19. Michael Crabtree at Seattle Seahawks
20. Percy Harvin at New Orleans Saints
21. Jermichael Finley at Philadelphia Eagles
22. Malcom Floyd at Kansas City Chiefs
23. Mike Wallace vs. Atlanta Falcons
24. Johnny Knox vs. Detroit Lions
25. Anquan Boldin at New York Jets
26. Lee Evans vs. Buffalo Bills
27. Dwayne Bowe vs. San Diego Chargers
28. Brent Celek vs. Green Bay Packers
29. Devin Hester vs. Detroit Lions
30. Visanthe Shiancoe at New Orleans Saints
31. Steve Smith (CAR) at New York Giants
32. Terrell Owens at New England Patriots
33. Donald Driver at Philadelphia Eagles
34. Wes Welker vs. Cincinnati Bengals
35. Jacoby Jones vs. Indianapolis Colts
36. Bernard Berrian at New Orleans Saints
37. Jabar Gaffney at Jacksonville Jaguars
38. Jeremy Maclin vs. Green Bay Packers
39. Steve Breaston at St. Louis Rams
40. Mike Williams (TB) vs. Cleveland Browns
41. Mohamed Massaquoi at Tampa Bay
42. Mike Sims-Walker vs. Denver Broncos
43. Hakeem Nicks vs. Carolina Panthers
44. Devrey Henderson vs. Minnesota Vikings
45. Santana Moss vs. Dallas Cowboys
46. Greg Olsen vs. Detroit Lions
47. Braylon Edwards vs. Baltimore Ravens
48. Devin Aromashodu vs. Detroit Lions
49. Jason Whitten at Washington Redskins
50. Mike Williams (SEA) vs. San Francisco 49ers